Methyl glycosides are identified as glycosyl donors for the synthesis of glycosides, disaccharides and oligosaccharides.
نویسندگان
چکیده
Stable methyl glycosides are identified as glycosyl donors in the presence of AuBr(3) in acetonitrile; a panel of aglycones comprising aliphatic, alicyclic, steroidal and sugar alcohols are examined successfully for the glycosylation reaction and methyl glycosides of di- and tri- saccharides are converted to corresponding tri- and tetra-saccharides exploiting salient features of our novel activation protocol.
منابع مشابه
Efficient synthesis of oligosaccharyl 1,2-O-orthoesters from n-pentenyl glycosides and application to the pentaarabinofuranoside of the mycobacterial cell surface.
Complex oligosaccharide syntheses employ the use of more than one glycosyl donor and hence, methods for the interconversion of glycosyl donors are highly valuable for the overall synthesis plan. Herein, n-pentenyl glycosides are efficiently converted to glycosyl 1,2-O-orthoesters in the presence of both acid and base sensitive functional groups. The identified protocol was found to be suitable ...
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ورودعنوان ژورنال:
- Chemical communications
دوره 18 شماره
صفحات -
تاریخ انتشار 2009